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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMTC2
All Species:
25.76
Human Site:
T743
Identified Species:
56.67
UniProt:
Q8N394
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N394
NP_689801.1
836
94130
T743
K
A
A
E
L
D
S
T
E
F
D
V
V
F
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086436
732
82592
E651
S
L
Y
N
M
M
G
E
A
Y
M
R
L
S
K
Dog
Lupus familis
XP_539701
927
103389
T834
K
A
A
E
L
D
S
T
E
F
D
V
V
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q56A06
836
94157
T743
K
A
A
E
L
D
N
T
E
F
D
V
V
F
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512438
838
94326
T745
K
A
A
E
L
D
S
T
E
F
D
V
V
F
N
Chicken
Gallus gallus
XP_416123
896
100813
T803
K
A
A
E
L
D
N
T
E
F
D
V
V
F
N
Frog
Xenopus laevis
Q6DCD5
836
94386
S743
K
A
A
E
L
D
S
S
E
F
D
V
V
F
N
Zebra Danio
Brachydanio rerio
XP_682966
813
91406
A728
E
F
D
V
V
F
S
A
A
H
M
L
R
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQE9
849
93644
Q762
R
A
A
A
L
A
P
Q
D
Y
T
L
Q
S
C
Honey Bee
Apis mellifera
XP_392318
822
89253
S738
R
A
A
E
L
S
R
S
D
Y
E
L
S
M
A
Nematode Worm
Caenorhab. elegans
Q20144
690
77719
I608
E
S
R
V
H
M
Q
I
G
S
C
H
A
K
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
86.4
84.6
N.A.
95.6
N.A.
N.A.
86.2
79.6
82.3
73.2
N.A.
36.5
41.9
20.8
N.A.
Protein Similarity:
100
N.A.
86.9
87.5
N.A.
97.8
N.A.
N.A.
92
86.6
89.9
84.5
N.A.
54.6
57.4
38.1
N.A.
P-Site Identity:
100
N.A.
0
93.3
N.A.
93.3
N.A.
N.A.
100
93.3
93.3
6.6
N.A.
20
26.6
0
N.A.
P-Site Similarity:
100
N.A.
20
100
N.A.
100
N.A.
N.A.
100
100
100
26.6
N.A.
46.6
66.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
73
73
10
0
10
0
10
19
0
0
0
10
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% C
% Asp:
0
0
10
0
0
55
0
0
19
0
55
0
0
0
0
% D
% Glu:
19
0
0
64
0
0
0
10
55
0
10
0
0
0
0
% E
% Phe:
0
10
0
0
0
10
0
0
0
55
0
0
0
55
0
% F
% Gly:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
10
0
10
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
55
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% K
% Leu:
0
10
0
0
73
0
0
0
0
0
0
28
10
0
0
% L
% Met:
0
0
0
0
10
19
0
0
0
0
19
0
0
10
0
% M
% Asn:
0
0
0
10
0
0
19
0
0
0
0
0
0
0
46
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
10
0
0
0
0
10
10
0
% Q
% Arg:
19
0
10
0
0
0
10
0
0
0
0
10
10
0
0
% R
% Ser:
10
10
0
0
0
10
46
19
0
10
0
0
10
19
10
% S
% Thr:
0
0
0
0
0
0
0
46
0
0
10
0
0
0
0
% T
% Val:
0
0
0
19
10
0
0
0
0
0
0
55
55
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
28
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _